Immune Response to Viruses: Innate immunity, Viral Recognition, Pattern Recognition Receptors, Expression of Immune Effector Activity, Viral Pathogenesis and Systems Approaches to Vaccination

The book offers a comprehensive and timely exploration of the complex interactions between viruses and the host immune system. Bringing together foundational principles and contemporary scientific insights, this volume examines how innate and adaptive immunity respond to viral invasion, how pathogens are recognized through pattern recognition receptors, and how immune effector mechanisms are activated and regulated during infection. The book provides detailed discussion of major respiratory viral infections, including SARS-CoV-2, RSV, and influenza, while also addressing their distinct impact on special populations such as newborns, pregnant women, and infants. It further investigates the diverse strategies by which viruses evade immune surveillance, interfere with antigen presentation, manipulate signaling pathways, and establish persistence or latency within the host. By integrating molecular immunology with viral pathogenesis, the volume offers readers a deeper understanding of the dynamic contest between host defense and viral adaptation. A notable strength of this work lies in its systems-based approach to vaccination and antiviral immunity. By examining immune signaling networks, interferon responses, viral immune evasion, and rational vaccine design, the book connects fundamental science with emerging therapeutic and preventive strategies. Rich in scope and scholarly relevance, this volume will be a valuable resource for researchers, students, clinicians, and academicians in immunology, virology, microbiology, and related biomedical sciences.