Lymphoma and Leukemia: Diagnosis, Treatment of Patients, Immunohistochemistry, Next-Generation Sequencing, Chemotherapy and Laboratory Techniques

The present book is a comprehensive and practice-oriented reference that brings together contemporary advances in the diagnosis, monitoring, and management of hematological malignancies. It integrates molecular biology, pathology, laboratory diagnostics, and therapeutic strategies within a single coherent framework. It systematically covers classical and modern diagnostic modalities, including immunohistochemistry, flow cytometry, cytogenetics, real-time PCR, and next-generation sequencing (NGS), with particular emphasis on measurable residual disease (MRD) assessment and its clinical significance. Detailed discussions on acute and chronic leukemias, lymphomas, plasma cell disorders, and therapy-related malignancies are complemented by in-depth coverage of pharmacogenomics, chemotherapy-associated toxicity, and stem cell transplantation. A distinctive strength of this work lies in its laboratory-focused approach, offering clear explanations of specimen handling, antibody panels, signal analysis, and interpretation of complex data. The inclusion of imaging technologies, confocal microscopy, and multiplex analyses further enhances its translational value. Designed for postgraduate students, laboratory professionals, pathologists, oncologists, and researchers, this book serves as both a foundational text and an advanced reference for evidence-based hematologic oncology and diagnostic medicine.