The present book explores the fascinating world of mass spectrometry and vibrational spectroscopy, two powerful tools reshaping pharmaceutical research and development. This comprehensive guide offers a meticulous exploration of cutting-edge techniques and their applications in pharmaceutical science, from molecular architecture determination to identifying environmental transformation products. The book begins with a robust introduction to mass spectrometry, unpacking fundamental principles such as sample introduction systems, ionization methods, and advanced ion detection systems like electron multipliers and conversion dynodes. It navigates through specialized methods such as electrospray, nanospray, and Chemical Ionization at Atmospheric Pressure (APCI), while shedding light on the intricacies of quadrupole ion traps and hybrid instruments. A distinct focus on vibrational spectroscopy—spanning infrared and Raman spectroscopy—equips readers with essential knowledge for sample preparation, instrumentation, and its use in molecular structure investigation. The integration of MSn techniques and advanced data processing further enhances the depth of this study. Highlighting practical applications, the book explores— Protein quantification and macromolecule analysis; Pharmaceutical and veterinary drug analysis; Imaging and identification of biotransformation products; Environmental and toxicological applications, including detecting pharmaceutical transformation products in water and the environment. Designed for researchers, professionals, and students, this volume not only covers technical intricacies but also emphasizes real-world applications in pharmaceutical analysis and beyond. Whether you're determining molecular weight, conducting accurate mass measurements, or employing MALDI MSI in pharmaceutical R&D, this book is an indispensable resource. Concluding with a synthesis of key findings and extensive references, Mass Spectrometry in Pharmaceutical Analysis bridges the gap between theory and practice, empowering readers to harness these technologies for innovative research and problem-solving.
Fhvcb
| DETAILS | |
| AUTHOR'S NAME | Mustafa Sajed Aloon, Alaa Hassan Yas, Hussein Tawfiq Abdel Abbas, Fawatim Fahem Jaber, Ahmed Hamdan Ali, Fadel Mamoun Fadel |
| ISBN | 978-93-95949-32-3 |
| EDITION | First |
| LANGUAGE | English |
| BINDING | Hardbound |
| SIZE | Demise |
| PAGES | 90 |
| PUBLISHER | Perception Publishing |
| Processor | |
| Description | The present book explores the fascinating world of mass spectrometry and vibrational spectroscopy, two powerful tools reshaping pharmaceutical research and development. This comprehensive guide offers a meticulous exploration of cutting-edge techniques and their applications in pharmaceutical science, from molecular architecture determination to identifying environmental transformation products. The book begins with a robust introduction to mass spectrometry, unpacking fundamental principles such as sample introduction systems, ionization methods, and advanced ion detection systems like electron multipliers and conversion dynodes. It navigates through specialized methods such as electrospray, nanospray, and Chemical Ionization at Atmospheric Pressure (APCI), while shedding light on the intricacies of quadrupole ion traps and hybrid instruments. A distinct focus on vibrational spectroscopy—spanning infrared and Raman spectroscopy—equips readers with essential knowledge for sample preparation, instrumentation, and its use in molecular structure investigation. The integration of MSn techniques and advanced data processing further enhances the depth of this study. Highlighting practical applications, the book explores— Protein quantification and macromolecule analysis; Pharmaceutical and veterinary drug analysis; Imaging and identification of biotransformation products; Environmental and toxicological applications, including detecting pharmaceutical transformation products in water and the environment. Designed for researchers, professionals, and students, this volume not only covers technical intricacies but also emphasizes real-world applications in pharmaceutical analysis and beyond. Whether you're determining molecular weight, conducting accurate mass measurements, or employing MALDI MSI in pharmaceutical R&D, this book is an indispensable resource. Concluding with a synthesis of key findings and extensive references, Mass Spectrometry in Pharmaceutical Analysis bridges the gap between theory and practice, empowering readers to harness these technologies for innovative research and problem-solving. |