Antimicrobial Screening: Multidrug-Resistant Strains, Traditional Medicine, Theoretical, Practical, and Technological Foundations

The book presents a timely and comprehensive study of one of the most urgent challenges in modern biomedical science: antimicrobial resistance. Bringing together theoretical insight, applied microbiology, and emerging technological approaches, this volume examines the rise of multidrug-resistant and extensively drug-resistant strains, the mechanisms underlying antibiotic resistance, and the evolving strategies needed to combat increasingly resilient pathogens. The book offers a detailed exploration of resistance mechanisms such as efflux pumps, target modification, drug metabolism, and the emergence of MDR and XDR strains, while also considering the epidemiology of resistant infections and the global burden of superbugs. It extends beyond conventional antibiotic frameworks to discuss promising alternatives, including phytochemicals, phage therapy, preventive interventions, and new directions in antimicrobial discovery. In doing so, it provides readers with a broad yet integrated understanding of the scientific, clinical, and public health dimensions of antimicrobial resistance. A distinctive strength of this work lies in its interdisciplinary approach. The volume examines virulence factors, secretion systems, quorum sensing, host immune responses, inflammasomes, Toll-like receptors, CRISPR-mediated adaptive immunity, gene delivery systems, and the challenges of vaccine development. By connecting microbial pathogenesis with therapeutic innovation, the book highlights both the complexity of resistant infections and the need for multifaceted scientific responses. Scholarly in scope and practical in significance, this book will serve as a valuable resource for students, researchers, academicians, clinicians, microbiologists, pharmacologists, and public health professionals. It contributes meaningfully to ongoing discussions on antimicrobial screening, resistance management, traditional and alternative therapies, and the future of infectious disease control in an era of escalating antimicrobial resistance.